Intracellular Accumulation as an Indicator of Cytotoxicity to Screen Hepatotoxic Components of Chelidonium majus L. by LC–MS/MS

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Chelidonium majus-Induced Acute Hepatitis

Medicinal herbs, defined as preparations concocted by an unauthorized layperson [1], are used widely in Asian countries because they are easily available and are believed to be harmless. Despite this belief, hepatitis, and even fulminant hepatitis, associated with medicinal herbs has been reported. According to previous reports, drug-induced liver injury accounts for 2~40% of all liver injury [...

متن کامل

Inhibition of mouse liver respiration by Chelidonium majus isoquinoline alkaloids.

The alkaloids from Chelidonium majus L. which had a significant inhibitory effect in mitochondrial respiration were those which contain a positive charge due to a quaternary nitrogen atom, i.e., chelerythrine, sanguinarine, berberine and coptisine, both with malate+glutamate or with succinate as substrates. When malate+glutamate was used as substrate, chelerythrine and berberine, which contain ...

متن کامل

A Quick Review of the Effects of Chelidonium majus L and Its Active Components on Health and Disease Treatment

Background: Using herbs for the treatment of diseases has a long history. Chelidonium majus from the family of Papaveraceae is one of the best-known and most widely used herbs used in traditional medicine. The aim of this study was to review its active components, as well as its therapeutic and toxic effects on body tissues. Methods: This short o...

متن کامل

Chelidonium majus--an integrative review: traditional knowledge versus modern findings.

Chelidonium majus L. (family Papaveraceae), or greater celandine, is an important plant in western phytotherapy and in traditional Chinese medicine. Crude extracts of C. majus as well as purified compounds derived from it exhibit a broad spectrum of biological activities (antiinflammatory, antimicrobial, antitumoral, analgesic, hepatoprotective) that support some of the traditional uses of C. m...

متن کامل

Evaluation of anti-inflammatory and analgesic activities of extracts from herb of Chelidonium majus L.

The aim of the study was to evaluate analgesic activity ("hot plate" test), anti-inflammatory activity (carrageenan-induced paw edema) and locomotor activity in rats under the influence of three fractions of Chelidonium majus herb extract: full water extract (FWE), protein enriched fraction (PEF), and non-protein fraction (NPF). Effects of the fractions on the level of chosen cytokines and thei...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Molecules

سال: 2019

ISSN: 1420-3049

DOI: 10.3390/molecules24132410